Home/Creams/CBD Moisturising Cream 50ml

CBD Moisturising Cream 50ml

R822.00 excl. VAT

Contains 100mg pure CBD per 50ml (56g) jar. No THC

Sku: CB01
    • 100mg pure CBD per jar (56g)
    • 100mg/jar is 2mg/ml
    • No THC
    • Same lipid bilayer moisturising technology as other OptoDerm crea...
    • 100mg pure CBD per jar (56g)
    • 100mg/jar is 2mg/ml
    • No THC
    • Same lipid bilayer moisturising technology as other OptoDerm creams
    • PenetrX transdermal delivery
    • Contains biomimetic moisturising factors – sodium PCA, sodium lactate, lactic acid, urea, glycine, ribose and inositol
    • Contains soothing peptide Acetyl Dipeptide-1 Cetyl Ester
    • Ideal as a post-procedure, anti-inflammatory cream


CBD accelerates cellular turnover in the epidermis, promoting enzyme, fillagrin and ceramide production – all of which are important for a healthy skin. At this concentration of CBD, genes are up and down-regulated (over 500 genes are affected!). Examples :


    • Up-regulation in fibroblasts enhances the production of collagen, elastin, hyaluronic acid and fibronectin
    • In sebocytes, lipid synthesis is either up- or down-regulated
    • In melanocytes, melanin production is down-regulated
    • Inflammation markers are down-regulated


With added neuro-peptide, N-Acetyl-Tyrosyl-Arginyl-Hexadecyl Ester – based on the Tyr-Arg peptide that occurs naturally in the body. This dipeptide was discovered by Japanese scientists at the University of Kyoto, and named kyotorphin because of its morphine- (or endorphin-) like analgesic activity. It works synergistically with CBD and:


    • stimulates the release of pro-endorphins (ß-endorphin and met-enkephalin), providing an exhilarating effect in the skin
    • relaxes and inhibits muscle contractions responsible for the appearance of expression wrinkles
    • reduces tactile and thermal sensitivity in the skin, especially post-procedure
    • reduces skin sensitivity to external factors such as chemical irritants.
Read more

Use once or twice a day, or as directed by your skincare professional. Apply over clean skin and on top of serums. Compatible with OptoDerm Serums.

This cream is not a medicine and is designed for skin care applications only. It is not designed to treat, cure or prevent any disease.

Ingredients: Aqua (Water), Ethylhexyl Palmitate, Cetyl Alcohol (and) Isostearyl Isostearate (and) Potassium Cetyl Phosphate (and) Cetyl Behenate (and) Behenic Acid, PEG-16 Macadamia Glycerides, C12-15 Alkyl Benzoate, Ethoxydiglycol, Cetyl Alcohol, Hydrogenated Olive Oil, Olea Europaea (Olive) Fruit Oil, Olea Europaea (Olive) Oil Unsaponifiables, Olive Oil PEG-7 Esters, Sodium Acrylates copolymer (AND) Lecithin, Hydroxylated Lecithin, Phosphatidylcholine, PPG-3 Benzyl Ether Ethylhexanoate, Urea, Sodium PCA, Sodium Lactate, Lactic Acid, Urea, Inositol, Ribose, Glycine, Caprylyl Glycol, Hydroxypropyl Cyclodextrin, Ethylhexylglycerin, Sodium Hyaluronate, Cannabidiol, Phenoxyethanol, EDTA, Parfum (Fragrance)

In the interests of producing the most effective products and keeping up with new generation actives, formulations and ingredients are subject to change without notice. The ingredients indicated on the product label are accurate as to the content of the product batch referred to.

Q. Is CBD legal and will it make me high?
A. It is legal, since CBD is a cannabinoid with no psychoactive activity. It will not make you high.

Q. Is CBD natural?
A. Yes, it is derived from hemp (cannabis sativa)

Q. What is the endocannabinoid system?
A. The endocannabinoid system (ECS) is a biological system composed of endocannabinoids, which are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors, and cannabinoid receptor proteins that are expressed throughout the mammalian central nervous system (including the brain and peripheral nervous system).

Q. Does the ECS exist in human skin?
A. Yes, in all cell types and especially the keratinocytes of the epidermis, which are responsible for the production of essential enzymes, filaggrin and ceramides necessary for a healthy skin barrier and good hydration.

Q. Does it work for psoriasis?
A. We do not make medical claims but CBD is implicated in controlling production of the inflammatory cytokines that result from an over-active immune system.






  1. Jani de Ridder (verified owner)

    The CBD cream is my most popular day and night cream at my clinic. Clients love the silky feel of it. It regulates the skin’s oil and moisture content perfectly.

  2. Nicola Du Toit (verified owner)

    CBD cream is my go-to product for Acne and Rosacea patients. Its speeds up the healing rate in the skin and restore the barrier. Reducing redness and pain patients might experience.

  3. Lindi Venter (verified owner)

    The Optoderm CBD cream has made a massive difference to the texture and feel of my skin. It is soft and soothing and smells lovely. I have a sensitive, reactive skin and this item works perfectly for my needs.

  4. Stokes (verified owner)

    I have used this cream for a little over a month now and have seen a massive improvement in my skin, particularly the redness surrounding acne prone areas. It’s also reduced the itching I tend to get around my nose and mouth. All in all, I am very happy with this product and will repurchase.

  5. Anneliese De Klerk (verified owner)

    Love this cream, does not leave my skin oily but moisturizes well. So glad I bought this cream. Looking forward to purchasing more products.

  6. Nadia Clenzos (verified owner)

    Honestly the best cream. My skin looks and feels smoother, softer and more hydrated. I have fewer breakouts and it has helped reduce redness, inflammation and sensitivity. Recommended by my skin specialist, so grateful!

  7. Mulalo (verified owner)

    The best cream and really helped with redness and inflammation. Thank u.

  8. Ilse Venter (verified owner)

    The CBD cream is a lovely cream, it made a major difference to the texture of my skin. I have a very sensitive skin and this cream did not irritate my skin at all.

  9. lvt@up.ac.za (verified owner)

    Product delivers sufficient and lasting moisturising.

  10. Dr. F Kimmie Dr. V Morar (verified owner)

    A very rich, calming moisturizer that doesn’t clog pores. Great for dry, oily or acne prone skin.

  11. Tamsin Haines (verified owner)

    ## Comment SPAM Protection: Shield Security marked this comment as “Pending Moderation”. Reason: Human SPAM filter found “111@” in “author_email” ##
    My dermatologist recommended this cream about a year ago and I have been using it ever since. It is the perfect moisturiser for my oily, acne-prone skin and has helped drastically in clearing my complexion.

  12. Mornay Camminga (verified owner)

    I have a very sensitive skin and my medical aesthetician placed me on the OptoDerm CBD Day /Night cream. I have been using it for a year and a half and am incredibly happy with the product. My skin feels soothed, well nourished and full of moisture.

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